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Updated: Feb 6, 2026

Validation of a Mouse Model to Disrupt LINC Complexes in a Cell-specific Manner
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Functional Analysis of LINC Complexes in the Skin

Iakowos Karakesisoglou1, Carmen Mroß2,3, Angelika A Noegel4,5

  • 1Department of Biosciences, University of Durham, Durham, UK.

Methods in Molecular Biology (Clifton, N.J.)
|August 25, 2018
PubMed
Summary

The LINC complex connects the nucleus to the cytoskeleton, crucial for cell structure and genome stability. This study details methods for analyzing LINC complex functions in skin cells using mouse models.

Keywords:
Directed cell migrationMouse embryonic fibroblastsNesprinPrimary fibroblastsPrimary keratinocytesSUN

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