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Neonate-omics: Charting the Unknown Immune Response in Early Life
Madeleine F Jennewein1, Audrey L Butler1, Galit Alter1
1The Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Abstract:
The study of neonatal immunology has been hampered by lack of access to infant samples. Novel sample sparing methods and systems-wide approaches have uniquely expanded this field, demonstrating that newborn immunity varies widely but converges over the first 3 months of life. During this important time window, environmental and genetic factors impact the infant immune system and can influence lifelong immunity.
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