Cannabinoids in dermatology: a scoping review.

Area of Science:

• Dermatology
• Pharmacology

Background:

• Cannabis and cannabinoid (e.g., CBD, THC) therapeutic uses are gaining attention with expanding legalization.
• While some cannabinoids are FDA-approved for specific conditions, their role in dermatology is not well-defined.

Purpose of the Study:

• To review the current literature on the therapeutic applications of cannabinoids for various skin diseases.

Main Methods:

• A comprehensive literature review was conducted to identify studies on cannabinoid use in dermatology.

Main Results:

• Cannabinoid products show potential for treating conditions including acne vulgaris, dermatitis (allergic contact, asteatotic, atopic), hidradenitis suppurativa, Kaposi sarcoma, pruritus, psoriasis, skin cancer, and cutaneous systemic sclerosis.
• Most available data are pre-clinical, with a significant lack of high-quality randomized controlled trials.

Conclusions:

• Cannabinoids demonstrate initial promise for treating numerous dermatologic conditions.
• Further robust pre-clinical research and large-scale randomized controlled trials are essential to establish the safety and efficacy of cannabinoids in dermatologic therapy.