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Updated: Feb 6, 2026

Author Spotlight: Characterizing Porous Materials for Aiding the Development of Robust Metal-Organic Frameworks with Adsorption Behavior
Published on: March 8, 2024
Ultrahigh efficient laser desorption ionization of saccharides by Ti-based metal-organic frameworks nanosheets
Yu-Jie Chang1, Shi-Shu Yang1, Xizhong Yu2
1Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.
Abstract:
We proposed some exfoliated Ti-based metal-organic frameworks (MOFs) nanosheets as matrices with ultrahigh ionization efficiency, free matrix background, significant dispersibility and acidic resistance. Combining the features between MOFs and 2-D nanomaterials, the NTU-9 nanosheets matrix also demonstrated suitable band gap energy and superior photoabsorption properties, much better than other representative MOFs. A wide range of small molecules that involving low mass region were also analyzed with NTU-9 nanosheets as the matrices in both positive-ion and negative-ion reflector modes. The ultra-efficient NTU-9 nanosheets matrix was successfully applied to serum for quantitative determination of glucose as a clinical diagnosis indicator of diabetes mellitus.
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