Diffusion-weighted magnetic resonance imaging of the paranasal sinuses: A systematic review

This was a systematic review of studies on the use of diffusion-weighted imaging (DWI) for paranasal sinus diseases. The applications of DWI were analyzed along with the main results, and conclusions were obtained by the investigators.

Databases were searched using the keyword "diffusion" combined with "sinonasal," "paranasal sinus," "maxillary sinus," "frontal sinus," "ethmoid sinus," and "sphenoid sinus," including only articles that were published from 2008 to 2018. Only original English language studies with sinonasal disease samples were selected.

Sixteen studies about various sinonasal diseases were included. The main objectives of most of the studies were related to the use of the apparent diffusion coefficient (ADC) in the differentiation of benign lesions and malignant neoplasms. We concluded that the ADC for malignant neoplasms is lower. Histologic features of samples evaluated in the studies were heterogeneous.

The ADC may improve the quality of the diagnostic hypothesis, particularly in differentiating benign and malignant diseases. Furthermore, the differences between certain types of lesions could be determined by using the ADC. However, further studies focusing on inflammatory diseases should be performed. Overall, DWI and the ADC are promising methods that can be incorporated into routine evaluations.