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Updated: Feb 6, 2026

Water in Oil Emulsions: A New System for Assembling Water-soluble Chlorophyll-binding Proteins with Hydrophobic Pigments
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Water in Oil Emulsions: A New System for Assembling Water-soluble Chlorophyll-binding Proteins with Hydrophobic Pigments

Published on: March 21, 2016

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Soluble resistance-related calcium-binding protein in cancers

Xiao Yu1, Jun Mao2, Salma Mahmoud1

  • 1Department of Pathology, College of Basic Medical Sciences, Dalian Medical University, Dalian 116044, China.

Clinica Chimica Acta; International Journal of Clinical Chemistry
|August 26, 2018
PubMed

Insights

Soluble resistance-related calcium binding protein (Sorcin) is an oncoprotein linked to high cancer levels and multidrug resistance (MDR). Understanding Sorcin

Area of Science:

  • Oncology
  • Molecular Biology
  • Biochemistry

Background:

  • Soluble resistance-related calcium binding protein (Sorcin) is an oncoprotein.
  • High Sorcin levels are observed in human cancers.
  • Sorcin contributes to multidrug resistance (MDR) in tumors.

Purpose of the Study:

  • To review and discuss the relationship between Sorcin and various tumors.
  • To summarize the regulatory mechanisms of Sorcin in cancer.
  • To highlight Sorcin as a potential therapeutic target.

Main Methods:

  • Literature review of studies on Sorcin and cancer.
  • Analysis of Sorcin's role in neoplastic processes.
  • Discussion of Sorcin's regulatory pathways.

Main Results:

  • Sorcin is implicated in key cancer processes like metastasis and apoptosis.
  • Sorcin expression is significantly elevated in multiple human cancers.
  • Sorcin's involvement in MDR is a critical finding.

Conclusions:

  • Sorcin plays a crucial role in cancer progression and drug resistance.
  • Further research into Sorcin's regulatory mechanisms is warranted.
  • Sorcin represents a promising molecular target for cancer therapy.
Keywords:
CancerMetastasisMultidrug-resistance (MDR)Soluble resistance-related calcium-binding protein (Sorcin)

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