Related Experiment Video
Updated: Feb 6, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Knowledge Gaps in Placebo Research: With Special Reference to Neurobiology
Paul Enck1, Bjoern Horing2, Ellen Broelz1
1Department of Internal Medicine VI: Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Tübingen, Germany.
Abstract:
This article addresses different ways to identify knowledge gaps in placebo research. Following a short description of the history of placebo research and our contributions, we describe the creation of the Journal of Interdisciplinary Placebo Studies (JIPS) literature database and compare its content (on a meta-level) with two other approaches to survey the current state of the art of placebo research: a bibliometric analysis of a (limited) selection of placebo papers, and the analysis of the content of all abstracts submitted to a 2017 placebo conference. We summarize this discussion with a critical assessment of these approaches and a perspective of future approaches in such placebo "meta"-analyses.
Related Concept Videos
The Placebo Effect
Gap Junctions
Gap Junctions
Special Staining Techniques
Inertial Frames of Reference
Non-inertial Frames of Reference

