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Updated: Jul 8, 2026

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

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Published on: July 1, 2014

Links between personality functioning and post-traumatic stress disorder symptoms: a network analysis.

Jürgen Fuchshuber^1,2, Henrik Kessler^3,4, Aram Kehyayan³

¹Department of Psychoanalysis and Psychotherapy, Medical University Vienna, Vienna, Austria.

European Journal of Psychotraumatology

|July 7, 2026

Summary

The link between personality functioning (PF) and post-traumatic stress disorder (PTSD) is specific, not just general distress. Targeting self-perception, trust, and emotion regulation may reduce PTSD symptoms in patients with PF impairments.

Keywords:

Funcionamiento de la personalidad OPD Personality functioning ansiedad anxiety análisis de redes depresión depression network analysis post-traumatic stress disorder somatic symptoms síntomas somáticos trastorno de estrés postraumático

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Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

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Published on: July 1, 2014

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Published on: December 6, 2024

Area of Science:

Psychiatry
Clinical Psychology
Network Analysis

Background:

Investigates the association between personality functioning (PF) and post-traumatic stress disorder (PTSD) symptoms.
Utilizes a network analytical approach in a large, naturalistic clinical sample.

Purpose of the Study:

Determine if the PF-PTSD link persists after controlling for depression, anxiety, and somatic symptoms.
Identify specific 'bridge' symptoms connecting PF and PTSD.

Main Methods:

Estimated a regularised partial correlation network including PF, PTSD, depression, anxiety, and somatic symptoms.
Analyzed data at total scale, subdomain, and item levels from the MEPP study (N=1899).

Main Results:

Confirmed a robust conditional association between PF and PTSD (E=.31).
Identified self-perception and relationship model as key PF subdomains linked to PTSD.
Found negative beliefs (PTSD) and self-esteem, interpersonal distrust, and affective dysregulation (PF) as central bridge nodes.

Conclusions:

The PF-PTSD relationship is specific and distinct from general distress.
Targeting negative self-perception, interpersonal trust, and affective regulation may reduce PTSD symptoms.
This approach is promising for patients with comorbid PTSD and PF impairments.