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Updated: Feb 6, 2026

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Flow Cytometry Purification of Mouse Meiotic Cells
Published on: April 15, 2011
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Atypical Localization of Malignant Plasma Cells in Non-Viable Cell Area on Flow Cytometry Light-Scatter Dot Plot
Tajana Juranovic1, Gary Harvey2, Jennie Johnson2
1Department of Internal Medicine, University Hospital Centre (KBC Rebro), Zagreb, Croatia.
The American Journal of Case Reports
|August 28, 2018
Summary
Plasma cells in bone marrow aspirates can show atypical scatter plots in older samples, appearing in the dead cell area. Checking this region for CD138 expression is crucial for diagnosing plasma cell dyscrasia.
Area of Science:
- Hematology
- Immunology
- Oncology
Background:
- Multi-parameter flow cytometry is vital for diagnosing plasma cell dyscrasias and assessing minimal residual disease.
- Plasma cell dyscrasias, including multiple myeloma, require accurate diagnostic methods.
- Flow cytometry analysis of bone marrow aspirates is a standard diagnostic procedure.
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