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Vaccinations

Vaccinations

Recombinant DNA

Recombinant DNA

Viral Recombination

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.

Homologous Recombination

Homologous Recombination

The basic reaction of homologous recombination (HR) involves two chromatids that contain DNA sequences sharing a significant stretch of identity. One of these sequences uses a strand from another as a template to synthesize DNA in an enzyme-catalyzed reaction. The final product is a novel amalgamation of the two substrates. To ensure an accurate recombination of sequences, HR is restricted to the S and G2 phases of the cell cycle. At these stages, the DNA has been replicated already and the...

Homologous Recombination

Homologous Recombination

Cancer Vaccines

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

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Related Experiment Video

Updated: Feb 6, 2026

Cell-Free Scaled Production and Adjuvant Addition to a Recombinant Major Outer Membrane Protein from Chlamydia muridarum for Vaccine Development

Cell-Free Scaled Production and Adjuvant Addition to a Recombinant Major Outer Membrane Protein from Chlamydia muridarum for Vaccine Development

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Zoster Vaccine Recombinant, Adjuvanted.

Kalvin Stoker¹, Terri L Levien¹, Danial E Baker¹

¹Washington State University, Spokane, USA.

Hospital Pharmacy

|August 28, 2018

Summary

The Formulary Monograph Service provides monthly drug monographs for Pharmacy & Therapeutics Committees, aiding in drug evaluation and utilization. Subscribers gain online access to customized monographs and drug utilization evaluations for informed decision-making.

Area of Science:

Pharmacology
Health Services Research

Background:

Pharmacy & Therapeutics Committees require timely drug information.
Evaluating new and investigational drugs is crucial for formulary management.

Purpose of the Study:

To describe the features and benefits of The Formulary Monograph Service.
To highlight the service's utility for healthcare professionals involved in drug selection and utilization.

Main Methods:

Monthly delivery of 5-6 detailed monographs on new or late-phase trial drugs.
Inclusion of 1-page summary monographs for pharmacy and nursing in-services.
Provision of comprehensive drug utilization evaluation/medication use evaluation (DUE/MUE).

Main Results:

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In Vitro Cellular Activity Evaluation of the Nanoemulsion Vaccine Adjuvant Ophiopogonin D

In Vitro Cellular Activity Evaluation of the Nanoemulsion Vaccine Adjuvant Ophiopogonin D

Published on: December 9, 2022

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Cell-Free Scaled Production and Adjuvant Addition to a Recombinant Major Outer Membrane Protein from Chlamydia muridarum for Vaccine Development

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Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection

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In Vitro Cellular Activity Evaluation of the Nanoemulsion Vaccine Adjuvant Ophiopogonin D

In Vitro Cellular Activity Evaluation of the Nanoemulsion Vaccine Adjuvant Ophiopogonin D

Published on: December 9, 2022

Subscribers receive well-documented drug information.

Online access to monographs is available.

Customization options cater to specific facility needs.

Conclusions:

The Formulary Monograph Service supports informed drug decision-making for P&T committees.
The service enhances drug utilization review and educational initiatives.