Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Measures of Central Tendency02:16

Measures of Central Tendency

21.2K
The "center" of a data set is also a way of describing location. The two most widely used measures of the "center" of the data are the mean (average) and the median. The words "mean" and "average" are often used interchangeably. The substitution of one word for the other is common practice. The technical term is "arithmetic mean" and "average" is technically a center location. However, in practice among non-statisticians,...
21.2K
Characteristics of Life01:23

Characteristics of Life

261.8K
Biology is a natural science that studies life and living organisms, including their structure, function, development, interactions, evolution, distribution, and taxonomy. The field's scope is extensive and divided into several specialized disciplines, such as anatomy, physiology, ethology, genetics, and many more. All living things share a few key traits, including cellular organization, heritable genetic material and the ability to adapt/evolve, metabolism to regulate energy needs, the...
261.8K
The Central Dogma01:25

The Central Dogma

139.9K
Overview
139.9K
Pain01:20

Pain

1.4K
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
1.4K
Characteristics of Fluids01:20

Characteristics of Fluids

8.2K
When a force is applied parallel to the top surface of a solid, it resists the applied force due to the internal frictional forces between the layers of the solid known as shearing resistance. However, when the force is removed, the shearing forces restore the original shape of the solid. Other deformation forces also cause temporary changes in shape if the forces are not beyond a threshold magnitude. Solids tend to retain their shape, making the study of their rest and motion easier. Beyond...
8.2K
Characteristics of BJT01:17

Characteristics of BJT

1.3K
The Bipolar Junction Transistor (BJT), specifically in a common-emitter configuration, exhibits distinct current-voltage characteristics crucial for understanding its behavior in electronic circuits. These characteristics are established through experimental measurements of voltage and current relationships.
For input characteristics, the base-emitter voltage is varied, maintaining a constant collector-emitter voltage. This setup reveals a Shockley-type dependence of the collector current on...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy of Steroid Supplementation After Temporomandibular Joint Arthrocentesis.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons·2020
Same author

Orthognathic Surgery as a Treatment for Temporomandibular Disorders.

Oral and maxillofacial surgery clinics of North America·2018
Same author

Evaluation of Early Postoperative Complications Following Tracheotomy.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons·2017
Same author

Intradisciplinary approach.

Oral surgery, oral medicine, oral pathology and oral radiology·2015
Same author

Atypical temporomandibular joint pain: a case report.

Oral surgery, oral medicine, oral pathology and oral radiology·2014
Same author

Increased vertical dimension effects on masseter muscle fiber phenotype during maturation.

The Angle orthodontist·2012
Same journal

Importance of Apparatus Scaling in Novel Object Recognition for Juvenile and Adult Rats.

Physiology & behavior·2026
Same journal

Chronic activity-based anorexia alters food intake microstructure in a time-dependent manner in female rats.

Physiology & behavior·2026
Same journal

Apelin receptor antagonist (ML221) facilitates memory reconsolidation in novel object recognition task.

Physiology & behavior·2026
Same journal

Are humans adapted to the world they have developed?

Physiology & behavior·2026
Same journal

50-kHz ultrasonic vocalization subtypes emitted by female rats anticipating same-sex social interaction.

Physiology & behavior·2026
Same journal

Sex-dependent behavioral and prefrontal BDNF mRNA responses to extinction training and short-term citalopram after fear conditioning in rats.

Physiology & behavior·2026
See all related articles

Related Experiment Video

Updated: Feb 6, 2026

Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing
09:16

Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing

Published on: February 16, 2017

17.5K

Mouse incising central pattern generator: Characteristics and modulation by pain.

Charles G Widmer1, Joyce Morris-Wiman2

  • 1Department of Orthodontics, Box 100444, JHMHSC, University of Florida, Gainesville, FL 32610-0444, USA.

Physiology & Behavior
|August 28, 2018
PubMed
Summary
This summary is machine-generated.

The central pattern generator (CPG) for mastication controls chewing rhythm and force. Muscle pain reduces incising force and load rates, supporting the Pain Adaptation Model.

Keywords:
Animal behaviorCentral pattern generatorHyperalgesiaMasticatory musclePhysiological adaptation

More Related Videos

Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain
07:27

Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain

Published on: July 18, 2016

9.2K
An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
14:56

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

Published on: January 27, 2010

22.1K

Related Experiment Videos

Last Updated: Feb 6, 2026

Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing
09:16

Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing

Published on: February 16, 2017

17.5K
Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain
07:27

Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain

Published on: July 18, 2016

9.2K
An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
14:56

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

Published on: January 27, 2010

22.1K

Area of Science:

  • Neuroscience
  • Biomechanics
  • Physiology

Background:

  • Mastication involves complex coordination of jaw muscles controlled by a central pattern generator (CPG).
  • Understanding CPG characteristics is crucial for elucidating jaw control mechanisms.

Purpose of the Study:

  • To characterize the CPG for mastication by recording mouse incising forces.
  • To evaluate how incising frequency and force direction affect CPG output.
  • To assess the impact of jaw closing muscle pain on CPG parameters.

Main Methods:

  • Recorded incising forces in mice using a 3D force transducer over 24 hours.
  • Analyzed force parameters (peak amplitude, load time, etc.) at various frequencies and force directions.
  • Evaluated effects of induced masseter muscle pain on incising parameters.

Main Results:

  • Incising force load time correlated significantly with incising frequency.
  • Higher incising frequencies resulted in decreased peak amplitude and increased load rates.
  • Jaw closing forces exhibited smaller peak amplitudes and load rates.
  • Muscle pain reduced incising peak amplitude and load rate.

Conclusions:

  • The masticatory CPG, similar to locomotor CPGs, controls rhythmicity and force parameters.
  • Unlike locomotor CPGs, masticatory CPG force amplitude decreases with increasing frequency.
  • Increased incising load rates with faster rhythms suggest larger motor unit recruitment.
  • Muscle pain diminishes CPG output to motoneurons, supporting the Pain Adaptation Model.