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Immunosuppression-lipid Metabolism Interplay and Medicinal Plants in Atherosclerosis: A Review
Fahimeh Moradi1, Robert D E Sewell2, Zahra Lorigooini1
1Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Abstract:
Atherosclerosis is a chronic arterial disease responsible for the majority of vascular-related deaths throughout the world. Immune cells and inflammation in conjunction with hyperlipidemia play a key role in atherosclerosis development. Regarding the low efficacy of the synthetic drugs and also the associated negative side effects which can adversely influence health-related quality of life, looking for natural, affordable and non-toxic substances seem necessary. Plant-derived natural products play a critical role in the prevention and treatment of atherosclerosis. In this review, we aimed to outline the most important medicinal herbs effective for atherosclerosis through the impact on immune system.
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