Related Experiment Video

Updated: Feb 5, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.7K

Effect of adenotonsillectomy for childhood obstructive sleep apnea on nocturnal heart rate patterns

Xiao Liu1, Sarah Immanuel1, Declan Kennedy2,3

  • 1School of Electrical and Electronic Engineering, The University of Adelaide, Adelaide, Australia.

Sleep
|August 31, 2018
PubMed

Insights

Adenotonsillectomy significantly reduces abnormal heart rate patterns in children with obstructive sleep apnea syndrome (OSAS), indicating improved cardiac autonomic modulation. This surgery offers a potential benefit for managing OSAS symptoms.

Area of Science:

  • Pediatric Sleep Medicine
  • Cardiology
  • Otolaryngology

Background:

  • Obstructive sleep apnea syndrome (OSAS) in children can impact autonomic nervous system function.
  • Cardiac autonomic modulation plays a crucial role in cardiovascular health.
  • Adenotonsillectomy is a common treatment for pediatric OSAS.

Purpose of the Study:

  • To evaluate the effect of adenotonsillectomy on cardiac autonomic modulation in children with OSAS.
  • To assess changes in nocturnal heart rate patterns following adenotonsillectomy.

Main Methods:

  • 354 children with OSAS were randomized to early adenotonsillectomy (eAT) or watchful waiting with supportive care (WWSC).
  • Nocturnal heart rate control was analyzed using overnight polysomnography (PSG) at baseline and 7 months.
  • The frequency of monotonous heart rate patterns during quiet sleep was quantified.

Main Results:

  • Children undergoing eAT showed a greater reduction in monotonous heart rate patterns post-surgery compared to the WWSC group.
  • Heart rate patterns normalized to similar levels in both groups when clinical PSG normalized.
  • Children with spontaneously normalized apnea-hypopnea index (AHI) had fewer heart rate patterns at baseline, suggesting milder obstruction.

Conclusions:

  • Adenotonsillectomy reduces monotonous heart rate patterns, indicating decreased cardiac autonomic modulation in children with OSAS.
  • Heart rate pattern analysis can quantify the impact of OSAS on the pediatric autonomic nervous system.
  • The study was registered at Clinicaltrials.gov (NCT00560859).
Abstract

More Related Videos

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

10.6K
Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood08:20

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood

Published on: October 2, 2019

12.6K

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
581
Regulation of Heart Rates01:31

Regulation of Heart Rates

The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
3.9K
Factors Influencing Heart Rate01:30

Factors Influencing Heart Rate

The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
6.7K
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
942
Cardiac Output I:Effect of Heart Rate on Cardiac Output01:19

Cardiac Output I:Effect of Heart Rate on Cardiac Output

Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
2.7K
Speciation Rates01:07

Speciation Rates

Overview
22.9K