Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Generator Voltage Control01:21

Generator Voltage Control

666
Generator voltage control is crucial for maintaining the stable operation of synchronous generators and wind turbines. In older models, a DC generator driven by the rotor delivers DC power to the rotor's field winding, and the power is transferred through slip rings and brushes. In the latest models, static or brushless exciters are used. Static exciters rectify AC power from the generator terminals and then transfer the DC power directly to the rotor. Brushless exciters, on the other hand, use...
666
Fixed Action Patterns01:06

Fixed Action Patterns

17.7K
A fixed action pattern (FAP) is a specific, hard-wired sequence of behaviors that occurs in response to an external stimulus, called a sign stimulus. The behavior is “fixed” because it is essentially unchangeable—proceeding similarly across individuals of a species every time it occurs.
17.7K
Responses to Salt Stress02:02

Responses to Salt Stress

14.6K
Salt stress—which can be triggered by high salt concentrations in a plant’s environment—can significantly affect plant growth and crop production by influencing photosynthesis and the absorption of water and nutrients.
14.6K
Patterns of Fever01:26

Patterns of Fever

3.9K
Before understanding the types and patterns of fever, it is essential to know its phases.
3.9K
Multi-input and Multi-variable systems01:22

Multi-input and Multi-variable systems

425
Cruise control systems in cars are designed as multi-input systems to maintain a driver's desired speed while compensating for external disturbances such as changes in terrain. The block diagram for a cruise control system typically includes two main inputs: the desired speed set by the driver and any external disturbances, such as the incline of the road. By adjusting the engine throttle, the system maintains the vehicle's speed as close to the desired value as possible.
In the absence of...
425
Responses to Heat and Cold Stress02:45

Responses to Heat and Cold Stress

14.8K
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
14.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Both genome instability and replicative senescence stem from the shortest telomere in telomerase-negative cells.

Nature communications·2026
Same author

CAMPER: mechanistic artificial intelligence for designing peptides that target MRSA persisters.

Nature communications·2026
Same author

A trade-off between stress resistance and tolerance underlies the adaptive response to hydrogen peroxide.

Cell systems·2025
Same author

Essentialome-Wide Multigenerational Imaging Reveals Mechanistic Origins of Cell Growth Laws.

bioRxiv : the preprint server for biology·2025
Same author

High-Throughput Measurement of Single-Fission Yeast Cell Volume Using Fluorescence Exclusion.

Methods in molecular biology (Clifton, N.J.)·2024
Same author

Changed life course upon defective replication of ribosomal RNA genes.

Genes & genetic systems·2023

Related Experiment Video

Updated: Feb 5, 2026

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
10:18

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

15.1K

Controllable stress patterns over multi-generation timescale in microfluidic devices.

Youlian Goulev1, Audrey Matifas1, Gilles Charvin1

  • 1Department of Developmental Biology and Stem Cells, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France; Institut National de la Santé et de la Recherche Médicale, Illkirch, France; Université de Strasbourg, Illkirch, France.

Methods in Cell Biology
|September 1, 2018
PubMed
Summary

This study introduces a microfluidics method for precise hydrogen peroxide (H2O2) stress control in budding yeast, enabling multi-generation cell growth monitoring and investigation of cellular adaptation to environmental stress.

Keywords:
AdaptationCell growthLive-cell imagingMicrofluidicsStress response

More Related Videos

Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices
07:53

Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices

Published on: April 1, 2016

8.0K
A Microfluidic Device with Groove Patterns for Studying Cellular Behavior
13:50

A Microfluidic Device with Groove Patterns for Studying Cellular Behavior

Published on: August 30, 2007

12.9K

Related Experiment Videos

Last Updated: Feb 5, 2026

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
10:18

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

15.1K
Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices
07:53

Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices

Published on: April 1, 2016

8.0K
A Microfluidic Device with Groove Patterns for Studying Cellular Behavior
13:50

A Microfluidic Device with Groove Patterns for Studying Cellular Behavior

Published on: August 30, 2007

12.9K

Area of Science:

  • Cellular biology
  • Biophysics
  • Microfluidics

Background:

  • Investigating cellular adaptive properties requires controlled environmental stress exposure.
  • Bulk experiments struggle with accurate temporal stress control.
  • Understanding cellular responses to oxidative stress is crucial.

Purpose of the Study:

  • To develop a microfluidics protocol for precise hydrogen peroxide (H2O2) stress control in budding yeast.
  • To enable single-cell resolution monitoring of cell growth over multiple generations under stress.
  • To create a method for generating ramping H2O2 stress for studying homeostatic systems.

Main Methods:

  • Utilized a microfluidics-based system for controlled H2O2 delivery.
  • Implemented single-cell resolution monitoring of budding yeast growth.
  • Developed a methodology for creating time-varying (ramping) H2O2 stress patterns.

Main Results:

  • Achieved tightly controllable H2O2 stress induction in budding yeast.
  • Successfully monitored cell growth with single-cell resolution over multiple generations.
  • Established a protocol for generating ramping H2O2 stress.

Conclusions:

  • Microfluidics offers precise control over cellular stress exposure.
  • The developed protocol facilitates in-depth study of cellular adaptation and homeostasis.
  • This method advances research into cellular responses to oxidative stress.