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Related Concept Videos

Chromatin Position Affects Gene Expression02:35

Chromatin Position Affects Gene Expression

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Chromatin is the massive complex of DNA and proteins packaged inside the nucleus. The complexity of chromatin folding and how it is packaged inside the nucleus greatly influences  access to genetic information. Generally, the nucleus' periphery is considered transcriptionally repressive, while the cell's interior is considered a transcriptionally active area. 
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An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
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[Plexiform cervical neurofibroma: about a case].

Lamiae Bouimetarhan1, Habib Bellamlih1, Issam En-Nafaa1

  • 1Service de Radiologie, Hôpital Militaire d'Instruction Mohammed V, Université Mohammed V, Rabat, Maroc.

The Pan African Medical Journal
|September 1, 2018
PubMed
Summary
This summary is machine-generated.

Plexiform neurofibroma, a rare tumor of peripheral nerves, is a key indicator of neurofibromatosis type 1 (NF1). This case highlights a cervical tumor revealing NF1 in a young girl.

Area of Science:

  • Oncology
  • Neurology
  • Genetics

Background:

  • Plexiform neurofibroma is a rare, benign peripheral nerve tumor.
  • It is pathognomonic for neurofibromatosis type 1 (NF1), also known as Von Recklinghausen disease.
Keywords:
MRINeurofibromatosisperineuriumplexiform

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  • Diagnosis can be challenging, especially in early stages or without overt NF1 signs.