Related Experiment Videos
[Value of preoperative study methods in midrectal cancer. Microscopy versus macroscopy]
Zentralblatt Fur Chirurgie
|January 1, 1986
Summary
Macroscopic tumor appearance in midrectal carcinoma is a valuable preoperative tool for predicting loco-regional spread and prognosis. Histological typing and grading offer limited predictive value for these outcomes.
Area of Science:
- Oncology
- Surgical Pathology
Context:
- Retrospective analysis of 110 midrectal carcinoma patients (1972-1983).
- Focus on preoperative data for curative, palliative, or exploratory surgery.
Purpose:
- To evaluate the predictive value of macroscopic and microscopic findings for loco-regional spread, lymph node involvement, prognosis, and recurrence in midrectal carcinoma.
Summary:
- Macroscopic tumor findings from rectoscopy significantly correlate with loco-regional spread (p=0.0001-0.0162) and prognosis (p=0.0001-0.0657).
- Histological typing, except for tubulo-papillary carcinoma (p=0.0153), and grading (p=0.0205) showed limited value for predicting spread or prognosis.
- Neither macroscopic nor microscopic assessment reliably predicted locally delimited recurrences.
- Macroscopic findings provided more comprehensive information on tumor status and prognosis compared to histological analysis (p=0.0470).
Impact:
- Highlights the importance of macroscopic tumor assessment in preoperative planning for midrectal cancer.
- Suggests prioritizing rectoscopic evaluation over detailed histological analysis for initial prognostic and staging information.
- Informs surgical strategy and patient counseling based on readily available preoperative data.