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Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
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Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes

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A retrospective systematic data review on the use of a polihexanide-containing product on burns in children

Guido Ciprandi1, Sharon Ramsay2, Ludmilla Budkevich3

  • 1Bambino Gesu' Children's Hospital, Research Institute Division of Plastic and Maxillofacial Surgery, Department of Surgery, Sant' Onofrio Square 4, 00165, Rome, Italy.

Journal of Tissue Viability
|September 2, 2018
PubMed

Insights

The Prontosan® range is safe for pediatric burn care, with minor adverse events like itching and rash. This study confirms its tolerability and effectiveness in promoting healing in children.

Area of Science:

  • Pediatric Burn Care
  • Wound Management
  • Dermatology

Background:

  • Physicians currently use Prontosan® products in children based on clinical experience, lacking specific safety data.
  • A retrospective review was conducted to assess the safety profile of Prontosan® in pediatric burn patients.

Purpose of the Study:

  • To evaluate the safety and tolerability of the Prontosan® range of products in children with burns.
  • To gather data on adverse events and healing outcomes in pediatric burn patients treated with Prontosan®.

Main Methods:

  • Retrospective data collection from patient medical records of newborns, infants, and children with burns treated with Prontosan®.
  • Analysis of safety based on reported adverse events, infections, and interactions in case report forms (CRFs).

Main Results:

  • The majority of burn patients (80.1%) were under four years old; 58.1% were boys.
  • Most burns were partial thickness (74.7%).
  • Minor adverse events (itching, rash, hypergranulating tissue) occurred in 5 children, with no severe events and favorable healing.

Conclusions:

  • The Prontosan® range is safe and well-tolerated for pediatric burn treatment.
  • Incorporating Prontosan® into pediatric burn care protocols supports effective wound cleansing and moist wound healing.
  • The study supports the use of Prontosan® for good healing outcomes in children's burn management.
Abstract

Keywords:
BurnsPaediatricsPolyhexanideProntosan(®)

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