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Related Experiment Video

Updated: Feb 5, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

Published on: September 25, 2009

Computational Fluid Dynamics Analysis and Correlation with Intraoperative Aneurysm Features.

Alberto Feletti^1,2, Xiangdong Wang³, Sandeep Talari³

¹Department of Neurosciences, Neurosurgery Unit, NOCSAE Modena Hospital, Modena, Italy. alberto.feletti@gmail.com.

Acta Neurochirurgica. Supplement

|September 2, 2018

Summary

This summary is machine-generated.

Computational fluid dynamics (CFD) analysis reveals low wall shear stress (WSS) alone doesn't predict aneurysm wall thickness. Combining WSS with pressure and flow patterns helps differentiate rupture-prone areas from atherosclerotic ones.

Keywords:

Aneurysm Computational fluid dynamics (CFD)Intraoperative Pressure Streamlines Wall shear stress (WSS)

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Area of Science:

Medical Imaging
Biomedical Engineering
Fluid Dynamics

Background:

Controversies exist regarding computational fluid dynamics (CFD) in aneurysm development and rupture.
Intraoperative visual findings are crucial for understanding aneurysm wall characteristics.

Purpose of the Study:

To analyze CFD data in patients undergoing aneurysm clipping.
To correlate CFD findings with intraoperative visual assessments of aneurysm walls.

Main Methods:

Used Hemoscope software to process images from 17 patients with 18 aneurysms.
Assessed pressure (P), wall shear stress (WSS) gradient/vectors, normalized WSS, and streamlines (SL) direction/velocity.
Compared CFD data with intraoperative visual findings across 39 aneurysm wall areas.

Main Results:

Low WSS correlated with thin, red aneurysm walls.
Low WSS combined with high P, diverging WSS vectors, and high SL velocity matched yellow, atherosclerotic walls.

Conclusions:

Low WSS is insufficient to determine aneurysm wall thickness.
Combining WSS with P and flow parameters can preoperatively distinguish atherosclerotic from thin, high-risk areas.
Dynamic changes in these parameters influence aneurysm features and rupture risk over time.