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Related Experiment Video

Updated: Feb 5, 2026

Gradient Echo Quantum Memory in Warm Atomic Vapor

Gradient Echo Quantum Memory in Warm Atomic Vapor

Published on: November 11, 2013

High spatial resolution BOLD fMRI using simultaneous multislice excitation with echo-shifting gradient echo at

Shi Su¹, Na Lu², Lin Jia³

¹Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.

Magnetic Resonance Imaging

|September 3, 2018

Summary

We developed a faster, high-resolution functional MRI (fMRI) technique using simultaneous multislice excitation and echo-shifting. This method improves blood oxygen level dependent (BOLD) imaging speed and quality at ultra-high fields.

Keywords:

Echo-shifting High spatial resolution SMS fMRI

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Last Updated: Feb 5, 2026

Gradient Echo Quantum Memory in Warm Atomic Vapor

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Cardiac Magnetic Resonance Imaging at 7 Tesla

Cardiac Magnetic Resonance Imaging at 7 Tesla

Published on: January 6, 2019

Area of Science:

Magnetic Resonance Imaging
Neuroimaging
Biophysics

Background:

Functional MRI (fMRI) is crucial for understanding brain function.
Conventional Gradient Echo (GRE) sequences face limitations in speed and spatial resolution for fMRI.
Ultra-high field (UHF) MRI offers increased sensitivity but requires advanced techniques to overcome challenges.

Purpose of the Study:

To introduce and validate an accelerated GRE sequence for high spatial resolution BOLD fMRI.
To combine simultaneous multislice (SMS) excitation with echo-shifting for enhanced acquisition.
To optimize scan parameters for maximal BOLD contrast and minimal power deposition at 7.0 Tesla.

Main Methods:

Developed an accelerated GRE sequence integrating SMS excitation and echo-shifting.
Performed simulations to optimize flip angle (9°) and acceleration factors (total of 10x).
Validated the technique in vivo with visual and motor tasks at 7.0T, comparing it to single-shot EPI.

Main Results:

Achieved geometric distortion-free BOLD images with 1.0x1.0x2.5 mm³ voxel size.
Demonstrated significant brain activation in visual and motor tasks, consistent with prior studies.
Optimized parameters yielded maximal BOLD contrast with low power deposition.

Conclusions:

The proposed accelerated GRE-fMRI technique enables high spatial resolution imaging at ultra-high fields.
It offers improved acquisition speed and BOLD sensitivity compared to conventional GRE methods.
This technique holds promise for advancing neuroimaging research and clinical applications.