Related Experiment Video

Updated: Feb 5, 2026

Three and Four-Dimensional Visualization and Analysis Approaches to Study Vertebrate Axial Elongation and Segmentation
12:59

Three and Four-Dimensional Visualization and Analysis Approaches to Study Vertebrate Axial Elongation and Segmentation

Published on: February 28, 2021

4.2K

Persistent fetal vasculature presenting with axial elongation and platyphakia

James Lin1, Manuel Paez-Escamilla1, Laila E Teira1

  • 1Ocular Oncology Service, Bascom Palmer Eye Institute, Miami, Florida.

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|September 4, 2018
PubMed

Insights

Persistent fetal vasculature (PFV) can mimic retinoblastoma in children. This case highlights atypical PFV presentations, including myopia and platyphakia, emphasizing the need for careful diagnosis.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Congenital Ocular Anomalies

Background:

  • Leukocoria in children necessitates ruling out retinoblastoma.
  • Persistent fetal vasculature (PFV) is a congenital anomaly mimicking retinoblastoma.
  • Typical PFV presents with microphthalmia, retrolental fibrovascular membrane, and cataract.

Observation:

  • A 9-month-old boy presented with leukocoria.
  • The patient exhibited axial myopia and platyphakia.
  • These features are atypical for classic PFV presentation.

Findings:

  • The case demonstrates an unusual presentation of PFV.
  • Axial myopia and platyphakia were key atypical features.
  • Distinguishing PFV from retinoblastoma remains critical.

Implications:

  • This case expands the differential diagnosis of leukocoria.
  • Awareness of atypical PFV presentations is crucial for accurate diagnosis.
  • Early and correct diagnosis prevents unnecessary treatment for retinoblastoma.

More Related Videos

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers08:48

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers

Published on: October 13, 2011

13.5K
Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation06:56

Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation

Published on: January 7, 2021

2.9K

Related Concept Videos

Transcription Elongation Factors02:35

Transcription Elongation Factors

Transcription elongation is a dynamic process that alters depending upon the sequence heterogeneity of the DNA being transcribed. Hence, it is not surprising that the elongation complex's composition also varies along the way while transcribing a gene.
The transcription elongation is regulated via pausing of RNA polymerase on several occasions during transcription. In bacteria, these halts are necessary because the transcription of DNA into mRNA is coupled to the translation of that mRNA...
14.0K
Transcription Elongation Factors02:35

Transcription Elongation Factors

4.8K
Axial and Appendicular Muscles01:18

Axial and Appendicular Muscles

Skeletal muscles, the key players in our body's movement, can be classified into two groups based on their location and function: axial muscles and appendicular muscles. These classifications reflect the primary roles the muscles play in the body's structure and movement.
Axial Muscles
Axial muscles, situated along the body's midline, are intricately connected to the axial skeleton, which includes the skull, spine, ribs, and sternum. These muscles facilitate facial expressions and...
2.8K
Overview of the Axial Skeleton01:09

Overview of the Axial Skeleton

The skeleton is subdivided into two major divisions—the axial skeleton and the appendicular skeleton. The axial skeleton forms the vertical, central axis of the body. It includes all of the bones of the head, neck, chest, and back. It protects the brain, spinal cord, heart, and lungs. It also serves as the attachment site for muscles that move the head, neck, and back and for muscles that act across the shoulder and hip joints to move their corresponding limbs.
The axial skeleton of the...
9.4K
General Case of Eccentric Axial Loading01:12

General Case of Eccentric Axial Loading

Unsymmetrical bending occurs when the bending moment applied to a structural member does not align with its principal axis. This misalignment leads to complex stress distributions and deflection patterns that differ from symmetrical bending, which are essential for designing structures to withstand different loading conditions.
Consider a member subjected to equal and opposite forces that are applied along a line that does not coincide with the member's neutral axis. In unsymmetrical...
513
Normal Strain under Axial Loading01:20

Normal Strain under Axial Loading

Normal strain under axial loading is an important concept in the field of mechanics of materials. Axial loading implies the application of a force along the axis of a material, like a column or bar. This force can either compress or stretch the material. In the context of axial loading, normal strain is the deformation experienced by the material in the direction of the loading force. It's calculated as the change in length divided by the original length of the material. This unitless ratio...
1.2K