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Related Concept Videos

Liver Histology01:27

Liver Histology

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The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
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The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
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The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
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The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
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Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
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Related Experiment Video

Updated: Feb 5, 2026

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach
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Laparoscopic repeat liver resection after open liver resection: A comparative study from a single-centre.

Taiga Wakabayashi1, Yuta Abe1, Osamu Itano2

  • 1Department of Surgery, Keio University School of Medicine, Tokyo, Japan.

Journal of Minimal Access Surgery
|September 5, 2018
PubMed
Summary

Laparoscopic repeat liver resection (LRLR) after open liver resection (OLR) for recurrent liver cancer is safe. Outcomes, including survival, were comparable to primary laparoscopic liver resection (LPLR).

Keywords:
Difficulty scorelaparoscopicminor liver resectionprevious open liver resectionrepeat liver resectionshort-term outcomes

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Area of Science:

  • Hepatobiliary surgery
  • Minimally invasive surgery
  • Surgical oncology

Background:

  • Technological advancements enable laparoscopic liver resection even with adhesions.
  • Laparoscopic repeat liver resection (LRLR) poses challenges, particularly after open liver surgery (OLR).
  • Evaluating LRLR outcomes after OLR for recurrent liver cancer is crucial.

Purpose of the Study:

  • To assess the safety and efficacy of LRLR following OLR.
  • To compare short-term outcomes and survival rates of LRLR versus laparoscopic primary liver resection (LPLR).

Main Methods:

  • Retrospective analysis of 62 patients undergoing minor laparoscopic liver resection.
  • Division into LRLR (n=13) and LPLR (n=49) groups.
  • Comparison of demographics, surgical details, short-term outcomes, recurrence-free survival (RFS), and overall survival (OS) for hepatocellular carcinoma (HCC) and colorectal liver metastases (CRLM).

Main Results:

  • Groups had comparable pre-operative liver function, histology, operative time, blood loss, complications, and hospital stay.
  • No significant differences in RFS or OS were observed between LRLR and LPLR groups for HCC and CRLM.
  • Similar outcomes were noted when stratified by difficulty.

Conclusions:

  • Minor LRLR following OLR is a safe and viable option.
  • LRLR demonstrates comparable outcomes to LPLR in selected cases.
  • This approach offers a minimally invasive alternative for recurrent liver cancer after prior open resection.