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Updated: Feb 5, 2026

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement
Published on: February 22, 2022
Spontaneous Coronary Artery Dissection in a Healthy Woman after Initiating a High-Intensity Interval Training Workout
Aaron A H Smith1, Moses Wananu1, Michelle D Carlson1
1Cardiology Division, Department of Medicine, Hennepin Healthcare, Minneapolis, Minnesota.
Abstract:
Although several risk factors are associated with spontaneous coronary artery dissection, strenuous activity is an uncommon risk factor for women. We report a case of a patient who developed spontaneous coronary artery dissection shortly after starting F45, a highly strenuous fitness program. As high-intensity exercise regimens become more mainstream, clinicians should more readily consider spontaneous coronary artery dissection in young patients with history of recent strenuous activity when presenting with symptoms concerning for acute coronary syndrome.
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