Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endotracheal Tube Extubation01:24

Endotracheal Tube Extubation

4.3K
Endotracheal tube extubation is a critical procedure in weaning patients from mechanical ventilation. It involves physically removing the oral or nasal endotracheal (ET) tube, marking the final step in liberating a patient from ventilatory support.
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
4.3K
Cleaning, Sterilization, and Disinfection01:30

Cleaning, Sterilization, and Disinfection

10.4K
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
10.4K
Endotracheal Intubation II: Nursing Management01:17

Endotracheal Intubation II: Nursing Management

2.7K
Endotracheal intubation is a critical procedure that can be lifesaving for many patients with respiratory distress or failure. The role of nursing in managing endotracheal tubes is pivotal, as it involves pre-intubation preparation, assisting during the procedure, and post-extubation care.
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
2.7K
Endotracheal Intubation I: Procedure01:15

Endotracheal Intubation I: Procedure

8.6K
Endotracheal or ET intubation is a critical medical procedure used to secure a patient's airway, often in acute respiratory distress, apnea, upper airway obstruction, ineffective clearance of secretions, high risk for aspiration, or during general anesthesia.
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
8.6K
Uterine Tubes01:16

Uterine Tubes

2.4K
The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
2.4K
Pinching-off of Coated Vesicles01:32

Pinching-off of Coated Vesicles

4.2K
Vesicle budding is orchestrated by distinct cytosolic proteins such as adaptor proteins, coat proteins, and GTPases. To initiate vesicle budding, membrane-bending proteins containing crescent-shaped BAR domains bind to the lipid heads in the bilayer and distort the membrane to form a protein-coated vesicle bud. Adaptors proteins such as AP2 for clathrin-coated vesicles can nucleate on the deformed membrane. Finally, coat proteins such as clathrin or COPI and COPII assemble into a coat forming...
4.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deep learning-based automatic identification model of main pancreatic duct in intraoperative ultrasonography.

Surgical endoscopy·2026
Same author

Advancing Precision Respiratory Physiology in Critical Care: A 10-Year Survey of the Lung Rescue Team.

Respiratory care·2026
Same author

Critical Care Anesthesiology Milestones 2.0: A Framework for Competency Assessment in Subspecialty Fellowship.

Journal of medical education and curricular development·2026
Same author

Rationale and protocol for time-based energy intake goals within an obesity care lifestyle intervention: Daily eating patterns for total health study.

Contemporary clinical trials·2026
Same author

CogniSNN: Enabling neuron-expandability, pathway-reusability, and dynamic-configurability in spiking neural networks.

Neural networks : the official journal of the International Neural Network Society·2026
Same author

Deciphering Early Oxidative Steps in Spirotetronate Biosynthesis Reveals a Two-Enzyme Cascade for Macrocyclic Lactone Formation.

Organic letters·2026

Related Experiment Video

Updated: Feb 5, 2026

Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine
07:00

Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine

Published on: February 26, 2019

10.1K

Silver-Coated Endotracheal Tubes Cleaned With a Mechanism for Secretion Removal.

Massimiliano Pirrone1,2, David Ae Imber1, Francesco Marrazzo1

  • 1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts.

Respiratory Care
|September 6, 2018
PubMed
Summary

Periodic cleaning of silver-coated endotracheal tubes (ETTs) did not reduce bacterial colonization or respiratory tract infections in mechanically ventilated patients. Further research is needed to optimize strategies for preventing ventilator-associated pneumonia.

Keywords:
airway managementairway obstructionbiofilmsintubationpneumoniaventilationventilator-associated pneumonia

More Related Videos

Fabrication of Thin Film Silver/Silver Chloride Electrodes with Finely Controlled Single Layer Silver Chloride
07:23

Fabrication of Thin Film Silver/Silver Chloride Electrodes with Finely Controlled Single Layer Silver Chloride

Published on: July 1, 2020

15.0K
Endotracheal Intubation in Mice via Direct Laryngoscopy Using an Otoscope
06:58

Endotracheal Intubation in Mice via Direct Laryngoscopy Using an Otoscope

Published on: April 5, 2014

33.0K

Related Experiment Videos

Last Updated: Feb 5, 2026

Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine
07:00

Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine

Published on: February 26, 2019

10.1K
Fabrication of Thin Film Silver/Silver Chloride Electrodes with Finely Controlled Single Layer Silver Chloride
07:23

Fabrication of Thin Film Silver/Silver Chloride Electrodes with Finely Controlled Single Layer Silver Chloride

Published on: July 1, 2020

15.0K
Endotracheal Intubation in Mice via Direct Laryngoscopy Using an Otoscope
06:58

Endotracheal Intubation in Mice via Direct Laryngoscopy Using an Otoscope

Published on: April 5, 2014

33.0K

Area of Science:

  • Critical Care Medicine
  • Infectious Diseases
  • Biomedical Engineering

Background:

  • Biofilm formation on endotracheal tubes (ETTs) is a primary cause of ventilator-associated pneumonia (VAP).
  • Silver-coated ETTs are designed to prevent biofilm and reduce VAP, but mucus can impede silver's antimicrobial activity.
  • This study investigated if periodic secretion removal could enhance silver-coated ETT efficacy.

Purpose of the Study:

  • To evaluate the effectiveness of a cleaning maneuver in reducing bacterial colonization on silver-coated ETTs.
  • To determine if this cleaning intervention decreases respiratory tract colonization in mechanically ventilated subjects.
  • To assess the impact on biofilm deposition and microbial load in tracheal secretions.

Main Methods:

  • A randomized controlled trial involving 39 mechanically ventilated subjects.
  • Subjects received either standard suctioning (control) or standard suctioning plus a cleaning maneuver every 8 hours (treatment).
  • ETT and tracheal aspirate samples were collected for microbiological analysis and biofilm quantification.

Main Results:

  • No significant reduction in bacterial colonization of ETTs was observed in the treatment group compared to the control group (P = .18).
  • Microbial load in ETTs and tracheal aspirates did not differ significantly between groups.
  • A trend towards decreased biofilm deposition was noted in the treatment group (P = .09).

Conclusions:

  • Periodic cleaning maneuvers did not decrease bacterial colonization of silver-coated ETTs.
  • The intervention did not lower respiratory tract colonization compared to standard suctioning.
  • The findings suggest that this cleaning method is not effective in enhancing the antimicrobial properties of silver-coated ETTs for VAP prevention.