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Updated: Feb 5, 2026

Plasma Lithography Surface Patterning for Creation of Cell Networks
Published on: June 14, 2011
Lift-off cell lithography for cell patterning with clean background
Cong Wu1, Xiongfeng Zhu, Tianxing Man
1Department of Mechanical and Biomedical Engineering, City University of Hong Kong, Hong Kong.
Abstract:
We developed a highly efficient method for patterning cells by a novel and simple technique called lift-off cell lithography (LCL). Our approach borrows the key concept of lift-off lithography from microfabrication and utilizes a fully biocompatible process to achieve high-throughput, high-efficiency cell patterning with nearly zero background defects across a large surface area. Using LCL, we reproducibly achieved >70% patterning efficiency for both adherent and non-adherent cells with <1% defects in undesired areas.
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