[Lyme disease in Perú. A clinical and epidemiological review]

Area of Science:

• Infectious Diseases
• Medical Microbiology
• Epidemiology

Background:

• Lyme disease, caused by Borrelia burgdorferi, is a significant tick-borne illness.
• Over the past two decades, Peru has seen reported cases and positive serology for Borrelia burgdorferi.
• Emerging evidence suggests the presence of novel Borrelia burgdorferi sensu lato species in South America.

Purpose of the Study:

• To critically review and synthesize available information on Lyme disease and Borrelia infection in Peru.
• To highlight the potential emergence of new Borrelia species in the region.
• To identify future research needs for understanding Borrelia epidemiology in Peru.

Main Methods:

• Comprehensive literature review of studies on Lyme disease and Borrelia in Peru.
• Analysis of serological data and reported clinical cases.
• Synthesis of current knowledge regarding Borrelia burgdorferi sensu lato in South America.

Main Results:

• Several studies indicate positive serology for Borrelia burgdorferi in Peru.
• Multiple cases of Lyme disease have been documented in Peru over the last 20 years.
• Preliminary data suggest the existence of new Borrelia burgdorferi sensu lato species in South America, with potential presence in Peru.

Conclusions:

• Lyme disease and Borrelia infections represent a growing concern in Peru.
• The potential discovery of new Borrelia species necessitates further investigation.
• Future studies should focus on genetic and microbiological analysis of Borrelia in vectors, reservoirs, and human cases to determine the extent and clinical impact of these findings.