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Related Concept Videos

Review and Preview01:10

Review and Preview

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In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
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Review and Preview01:13

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Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
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Ethics in Research01:56

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Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
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Updated: Feb 5, 2026

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
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Colorectal Lymphoma: A Review.

Nathan D Gay1, Andy Chen1, Craig Y Okada1,2

  • 1Department of Hematology/Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon.

Clinics in Colon and Rectal Surgery
|September 7, 2018
PubMed
Summary

Primary colorectal non-Hodgkin lymphoma (NHL) is rare and distinct from nodal lymphoma. Understanding its subtypes is crucial for effective management and achieving durable remissions.

Keywords:
extranodalgastrointestinallarge bowelprimary colorectal lymphoma

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Area of Science:

  • Gastroenterology
  • Hematology
  • Oncology

Background:

  • Primary colorectal non-Hodgkin lymphoma (NHL) is an uncommon condition.
  • It requires differentiation from systemic nodal lymphoma due to unique clinical presentations.
  • Histologic subtypes of colorectal NHL exhibit varied clinical behaviors and treatment responses.

Purpose of the Study:

  • To review the current understanding of primary colorectal lymphoma subtypes.
  • To propose management algorithms for these rare lymphomas.

Main Methods:

  • Literature review of primary colorectal non-Hodgkin lymphoma.
  • Analysis of clinical behavior and treatment outcomes for different histologic subtypes.
  • Development of evidence-based management strategies.

Main Results:

  • Colorectal NHL presents unique clinical expectations and management considerations.
  • Different NHL subtypes involving the colon have distinct prognoses.
  • Effective management strategies depend on accurate histologic subtyping.

Conclusions:

  • Accurate diagnosis and subtyping of primary colorectal lymphoma are essential.
  • Tailored management algorithms can improve outcomes for patients with colorectal NHL.
  • Further research into specific subtypes may optimize treatment protocols.