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Rab GTPases in Osteoclastic Endomembrane Systems.

Michèle Roy1, Sophie Roux1

  • 1Division of Rheumatology, Faculty of Medicine, University of Sherbrooke, 3001, 12th Avenue North, Sherbrooke, PQ, Canada.

Biomed Research International
|September 7, 2018
PubMed
Summary

Small GTPases, including Rab proteins, regulate bone-resorbing osteoclasts (OCs). These GTPases control OC differentiation, survival, and activity through vesicular trafficking and degradation pathways.

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