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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

Updated: Feb 5, 2026

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice
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Corneal hysteresis and glaucoma.

Liang Liang1, Ran Zhang2, Li-Ye He2

  • 1Department of Ophthalmology, Yichang Central People's Hospital, The First College of Clinical Medical Science, China Three Gorges University, Yichang, 443003, People's Republic of China. liangliang419519@163.com.

International Ophthalmology
|September 7, 2018
PubMed
Summary
This summary is machine-generated.

Corneal hysteresis (CH) measures corneal biomechanics and is lower in glaucoma patients. Lower CH values indicate increased glaucoma risk and progression, aiding in diagnosis and treatment strategies.

Keywords:
BiomechanicsCorneal hysteresisGlaucoma

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Area of Science:

  • Ophthalmology
  • Biomechanical Engineering
  • Glaucoma Research

Background:

  • Corneal hysteresis (CH) quantifies the cornea's ability to absorb and dissipate energy.
  • CH is a crucial biomechanical parameter influenced by corneal shape and individual variations.
  • Normal CH values in healthy adults average around 11 mmHg.

Purpose of the Study:

  • To review and summarize the characteristics of corneal hysteresis (CH).
  • To investigate the relationship between corneal hysteresis and glaucoma.
  • To assess CH as a diagnostic and prognostic indicator for glaucoma.

Main Methods:

  • A comprehensive literature search was conducted on PubMed.
  • Keywords used included "corneal hysteresis", "glaucoma", and "biomechanics".
  • Studies published in English up to March 2018 were included.

Main Results:

  • All glaucoma types exhibited lower CH values compared to healthy individuals.
  • Lower CH is linked to thinner retinal nerve fiber layer, larger cup/disk ratio, and optic disc defects.
  • CH and intraocular pressure interact synergistically, influencing glaucoma progression.

Conclusions:

  • CH serves as a predictor for glaucoma risk and progression.
  • CH may help assess the impact of corneal thickness on intraocular pressure.
  • The clinical significance of CH in glaucoma diagnosis and management is expected to grow.