Interventional cardiology: from balloons to stents … and back?

The treatment of coronary artery disease has seen rapid change following the invention of percutaneous coronary intervention (PCI). Since its introduction and widespread adoption for the treatment of coronary artery disease, efforts have been underway to minimise both the acute and long-term complications associated with the procedures, resulting in varying degrees of success over the years. These measures have taken many forms, from the adjunctive drug treatment regimen that patients receive before, during and after procedures to the actual mechanical intervention to the vessels themselves. The current gold standard in the interventional field is second-generation drug-eluting stents. However, with ongoing research into new technologies and trials underway in absorbable and non-stent treatments, it may soon be possible to achieve the goal of leaving no long-term physical implant behind in the artery. This could overcome issues with inflammation associated with permanent foreign body implants and prove less limiting for future treatment if needed.