Related Experiment Video
Updated: Feb 5, 2026

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA
Published on: July 15, 2011
THE STRUCTURE OF DNA CHROMOCENTRES IN MOUSE IN SILICO AND IN SITU. LINE AND ERV FRAGMENTS ARE AN OBLIGATORY
Abstract:
Constitutive heterochromatin in higher eukaryotes is located in the primary chromosomal strangulation (centromeres and pericentromeres) and subtelomeric regions of chromosomes. In house mouse constitutive chromatin formes structures in the nuclei of cells, brightly colored with DAPI. It is known that the constitutive heterochromatin is enriched with large tandem repeats, however, its exact composition is unknown. In this paper chromocenters were studied using several approaches: cloning and sequencing by Sanger, as well as by high-throughput sequencing. We have shown that DNA components of chromocenters and constitutive chromatin are full-length endogenous retroviruses (ERV) and a 2 kbp fragment of the 3R-end of the LINE.
Related Concept Videos
DNA Replication
Replication in Prokaryotes
DNA replication...
DNA-only Transposons
The donor site from where the transposon is excised is either degraded or...
DNA Helicases
From DNA to Protein
The DNA Helix
DNA Topoisomerases
Types and Mechanism of action
Topoisomerases are divided into two main types. ...

