Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Large brain metastasis not shown by computerized tomography.

J A Hall, M H Lipper, G M Mire

    Southern Medical Journal
    |September 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Equipping for risk: Lessons learnt from the UK shale-gas experience on assessing environmental risks for the future geoenergy use of the deep subsurface.

    The Science of the total environment·2024
    Same author

    Risk of hospitalisation or death in households with a case of COVID-19 in England: an analysis using the HOSTED data set.

    Public health·2022
    Same author

    Women's experiences of early pregnancy assessment unit services: a qualitative investigation.

    BJOG : an international journal of obstetrics and gynaecology·2021
    Same author

    HOSTED-England's Household Transmission Evaluation Dataset: preliminary findings from a novel passive surveillance system of COVID-19.

    International journal of epidemiology·2021
    Same author

    Limits on the Existence of sub-MeV Sterile Neutrinos from the Decay of ^{7}Be in Superconducting Quantum Sensors.

    Physical review letters·2021
    Same author

    Impacts of operating conditions on efficiency of electrokinetically enhanced filtration for de-watering of orange juice and malt extract.

    Food chemistry·2020
    Same journal

    SMA's 6th Annual Physicians-in-Training Leadership Conference Abstract Presentations.

    Southern medical journal·2026
    Same journal

    Potential Impact of Lower Federal Loan Availability on Medical Education in Appalachia.

    Southern medical journal·2026
    Same journal

    Experiential Mentorship Skills Training: The Effect on Real-Life Mentoring.

    Southern medical journal·2026
    Same journal

    Social Pressure: How Early Social Context Shapes Career Interest in Medicine.

    Southern medical journal·2026
    Same journal

    Comparing Speed and Accuracy of Artificial Intelligence Large Language Models on the Orthopedic In-Training Examination.

    Southern medical journal·2026
    Same journal

    Don't Wait to Talk about Weight: A 2-Hour Interactive Curriculum Improves Medical Student Skills with Weight Management.

    Southern medical journal·2026
    See all related articles

    Computed tomography (CT) scans failed to detect brain metastases in a small cell lung cancer patient. Autopsy revealed two large metastatic lesions, highlighting limitations in CT imaging for detecting certain metastatic cancers.

    Area of Science:

    • Oncology
    • Radiology
    • Pathology

    Background:

    • Small cell lung cancer (SCLC) is an aggressive malignancy with a high propensity for metastasis.
    • Cerebral metastases are common in SCLC and significantly impact patient prognosis.
    • Accurate detection of brain metastases is crucial for treatment planning and management.

    Observation:

    • A patient with metastatic SCLC presented with no apparent intracranial metastases on cranial computed tomography (CT) and contrast-enhanced CT scans.
    • Despite negative imaging findings, the patient's condition deteriorated rapidly.
    • Post-mortem examination revealed two substantial intracerebral metastatic lesions.

    Findings:

    • Computed tomography (CT) imaging, including contrast-enhanced scans, demonstrated a failure to visualize significant intracerebral metastatic disease in this SCLC case.

    Related Experiment Videos

  • Autopsy findings confirmed the presence of sizable metastatic foci in the brain, contradicting the negative CT results.
  • This discrepancy suggests potential limitations of CT in detecting certain types or sizes of brain metastases.

    • Implications:

    • The findings underscore the potential for false-negative results with CT imaging in the detection of brain metastases from SCLC.
    • Consideration of alternative or supplementary diagnostic modalities may be warranted in cases with high clinical suspicion for cerebral metastases despite negative CT.
    • Further research into the factors influencing CT visualization of brain metastases is needed to improve diagnostic accuracy in neuro-oncology.