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Mesenteric Panniculitis (MP): A Frequent Coincidental CT Finding of Debatable Clinical Significance

Özlem Gögebakan1, Martin A Osterhoff2, Thomas Albrecht1

  • 1Department for Radiology and Interventional Therapy, Vivantes Klinikum Neukölln, Berlin, Germany.

Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|September 7, 2018
PubMed
Abstract

Insights

Mesenteric panniculitis (MP) is a common CT finding of unclear cause, often asymptomatic. While typically benign, distinguishing it from lymphoma is crucial, and its clinical significance is debated.

Area of Science:

  • Radiology
  • Gastroenterology
  • Pathology

Background:

  • Mesenteric panniculitis (MP) involves chronic inflammation of intestinal adipose tissue with unknown etiology.
  • It predominantly affects middle-aged to older men and is often an incidental abdominal CT finding.
  • The condition's prevalence may be underestimated due to underreporting.

Purpose of the Study:

  • To review the literature on mesenteric panniculitis (MP).
  • To discuss its CT characteristics, differential diagnoses, and clinical significance.
  • To explore its association with other diseases and potential therapeutic options.

Main Methods:

  • A comprehensive literature review was conducted using PubMed.
  • Search terms included "mesenteric panniculitis", "panniculitis mesenterialis", "CT", "imaging", and "sclerosing mesenteritis".
  • Case reports and cohort studies were included in the analysis.

Main Results:

  • Mesenteric panniculitis (MP) is a frequent incidental finding on abdominal CT, with characteristic signs.
  • Malignant lymphoma is the primary differential diagnosis, posing challenges in distinction.
  • While associations with other diseases and malignancy have been suggested, evidence remains inconclusive.

Conclusions:

  • MP is a common, often asymptomatic, CT finding requiring differentiation from lymphoma.
  • Its clinical relevance and association with other conditions, including malignancy, are subjects of ongoing scientific debate.
  • Therapeutic options like glucocorticoids and tamoxifen exist for rare symptomatic cases.

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