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Updated: Feb 5, 2026
05:26
Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
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Right ventricular function in patients presenting with non-ST-segment elevation myocardial infarction undergoing an
Ahmed Shawky Elserafy1, Ahmed Nabil1, Ali Ali Ramzy2
1Department of Cardiology, Ain Shams University, Egypt.
Summary
Right ventricular dysfunction is common in non-ST elevation myocardial infarction (NSTEMI) and improves after percutaneous coronary intervention (PCI). Assessing right ventricular function using tricuspid annular plane systolic excursion (TAPSE) is recommended for NSTEMI patients.
Area of Science:
- Cardiology
- Cardiac Imaging
- Interventional Cardiology
Background:
- Right ventricular (RV) involvement in ST-segment elevation myocardial infarction (STEMI) increases mortality.
- Data on RV affection in non-ST-segment elevation myocardial infarction (NSTEMI) is limited.
Purpose of the Study:
- To evaluate RV function in NSTEMI patients undergoing invasive procedures.
- To assess the impact of percutaneous coronary intervention (PCI) on RV function in NSTEMI.
Main Methods:
- 150 NSTEMI patients eligible for PCI were divided into normal and impaired RV function groups based on tricuspid annular plane systolic excursion (TAPSE) < 17 mm.
- RV function was assessed using TAPSE at baseline and 3-month follow-up.
- Independent predictors of RV dysfunction were identified through multivariate analysis.
Main Results:
- RV dysfunction was observed in 61.3% of NSTEMI patients.
- TAPSE showed significant improvement at 3 months post-PCI compared to baseline (15.45 ± 3.21 mm vs. 17.09 ± 4.17 mm).
- Impaired RV function patients demonstrated significant TAPSE improvement (13.62 ± 2.58 mm vs. 17.16 ± 3.64 mm, p=0.008).
Conclusions:
- RV dysfunction is prevalent in NSTEMI, defined by TAPSE < 17 mm.
- Successful PCI leads to significant improvement in RV function (TAPSE) at 3 months.
- Routine assessment and monitoring of RV function in NSTEMI patients are recommended.
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