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Two-Dimensional X-Ray Angiography to Examine Fine Vascular Structure Using a Silicone Rubber Injection Compound
Published on: January 7, 2019
Vascular conspicuity differs among injection protocols and scanner types for canine multiphasic abdominal computed
Florence Thierry1, Jennifer Chau2, Mariano Makara2
1The Royal (Dick) School of Veterinary Studies and Roslin Institute, The University of Edinburgh, Roslin, EH25 9RG, UK.
Comparing canine abdominal CT angiography protocols, the fixed-injection-duration method offers the best balance for vascular enhancement on various scanners. The test-bolus protocol excels on advanced 64-row scanners for optimal vascular conspicuity.
Area of Science:
- Veterinary Radiology
- Diagnostic Imaging
- Comparative Medical Imaging
Background:
- Multiphasic multidetector computed tomographic angiography (MDCT) is crucial for diagnosing canine abdominal vascular disorders.
- Existing protocols (test-bolus, bolus-tracking, fixed-injection-duration) have varying advantages and limitations regarding speed, accuracy, and reproducibility.
- Scanner technology, specifically the number of detector rows, may influence protocol performance.
Purpose of the Study:
- To compare the vascular conspicuity of three MDCT angiography protocols in canine abdominal imaging.
- To evaluate the impact of different MDCT scanner types (4, 16, and 64-row) on study quality.
- To identify the optimal protocol for canine abdominal vascular imaging across diverse CT scanner capabilities.
Main Methods:
- A multicentric study involving retrospective (30 dogs) and prospective (21 dogs) data acquisition.
- Comparison of test-bolus, bolus-tracking, and fixed-injection-duration protocols across 4, 16, and 64-row MDCT scanners.
- Blinded reader assessment of arterial and portal venous phase conspicuity for main abdominal vessels.
Main Results:
- The fixed-injection-duration protocol demonstrated superior combined arterial and portal vascular conspicuity on slower (4/16-row) scanners.
- The test-bolus protocol yielded the best overall vascular conspicuity on high-speed (64-row) MDCT scanners.
- Arterial phase image quality was significantly enhanced on 64-row MDCT compared to 4/16-row scanners.
Conclusions:
- The fixed-injection-duration protocol represents a practical compromise, offering good vascular enhancement and reproducibility on both low and high-detector-row scanners.
- The test-bolus protocol is optimal for achieving the highest vascular conspicuity when using advanced 64-row MDCT technology.
- Protocol selection should consider scanner capabilities to optimize diagnostic accuracy for canine abdominal vascular disorders.
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