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Updated: Feb 5, 2026

Purification of the Sarco-Endoplasmic Reticulum Ca2+-ATPase from Rabbit Muscle
Published on: March 21, 2025
FLUORESCENT MICROSCOPY IDENTIFICATION OF THE EXPRESSION OF a2 AND b1 NA +/K+-ATPase, a1S (L-TYPE), ÑÀ2+-CHANNEL,
Abstract:
The experiments of modeling hypogravity using fluorescent microscopy have shown a decrease of expression of b1 of Na +/K+-ATPase and Ca2+-ATPase subunits and the increase in the insensitivity of synthesis of a1S subunit of the L-type Ca2+-channel of the plasmatic membrane, whereas the synthesis of a2 subunit of Na+/K+-ATPase does not change. In «fast» muscle only observed similar for «slow» muscle decrease in the expression of b1 subunit without changing other parameters were studied. However, the decrease in fluorescence b1 subunit due to spread of data was not statistically significant. Thus hypogravity adversely affects the functioning primarily skeletal muscles, providing static load.
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