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Multilevel spinal reconstruction in pediatric patients under 4 years old with non-congenital pathology (10-year
Alexander Yu Mushkin1,2, Denis G Naumov3, Valery A Evseev3
1Saint-Petersburg Research Institute of Phthisiopulmonology, Politechnicheskaya str. 32, Saint Petersburg, Russia, 194064. aymushkin@mail.ru.
Insights
Anterior spinal fusion using titanium mesh cages with bone grafts (TMC+BG) in young children is safe and effective. This method reduces operation time, blood loss, and complication rates compared to bone grafts alone for multilevel spinal reconstructions.
Area of Science:
- Pediatric Orthopedics
- Spinal Surgery
- Biomaterials in Spine Fusion
Background:
- Multilevel spinal reconstructions are complex procedures in young children.
- Deformities like kyphosis necessitate surgical intervention.
- Evaluating anterior fusion techniques is crucial for optimizing outcomes.
Purpose of the Study:
- To assess the short- and long-term outcomes of anterior fusion options in pediatric multilevel spinal reconstructions.
- To compare titanium mesh cage with bone graft (TMC+BG) versus bone graft (BG) only for anterior fusion.
Main Methods:
- Retrospective analysis of 45 patients under 4 years old undergoing spinal reconstruction for spondylitis or tumors.
- Comparison of outcomes between TMC+BG (19 patients) and BG only (26 patients) groups.
- Data collected included clinical and radiographic parameters, with an average follow-up of 5 years 10 months.
Main Results:
- Deformity correction was similar between groups.
- The TMC+BG group showed significantly less operation time, blood loss, and time for anterior bone block formation.
- The TMC+BG group had a lower complication rate (2 vs. 8 cases), including pseudoarthrosis and graft resorption.
Conclusions:
- Multilevel spinal reconstruction in young children is a safe and effective procedure.
- Anterior fusion with TMC+BG offers advantages over bone autograft alone, reducing complications and surgical burden.
- TMC+BG is a superior anterior fusion option for pediatric spinal reconstructions.
Purpose:
To evaluate the influence of anterior fusion option on the short- and long-time outcomes on multilevel spinal reconstructions in young children.
Methods:
Forty-five patients aged under 4 years old (2 years 2 months ± 11 months in average) underwent spinal reconstruction due to tuberculosis spondylitis (35), pyogenic spondylitis (9) and spinal tumors (1) complicated by angular kyphosis exceeded 20° (49.2° ± 14.3° in average). All lesions involved two or more spinal motion segments. Clinical and radiographic data were compared in two groups depended on the types of anterior fusion: titanium mesh cage with bone graft (TMC + BG) (19 patients) and cortical BG only (26). The average follow-up was 5 years 10 months ± 2 years 8 months (min = 3 years; max = 12 years).
Results:
The deformity correction was similar in groups. The operation time and blood loss were less in TMC + BG group (p = 0.001) as a times for anterior bone block formation (p < 0.001) and posterior instrumentation removal (p = 0.003). Ten late post-op complications registered include disease's recurrence (1), pseudoarthrosis (6), deformity progression (1) and graft resorption (1). The complication rate was less in TMC + BG than in BG group: two and eight cases consequently, p = 0.024.
Conclusions:
Multilevel spinal reconstruction in early aged patients is safe and effective procedure. The anterior fusion by TMC with bone autograft has advantages of reducing blood loss, operation time, time for anterior block formation and complications rate compared with bone autograft only. These slides can be retrieved under Electronic Supplementary Material.
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