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Neuropathy and Other Risk Factors for Lower Extremity Amputation in People with Diabetes Using a Clinical Data
Shaima Alothman1, Aqeel Alenazi, L Russ Waitman
1Dep. of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, 3901 Rainbow Blvd., MS 2002, Kansas City, KS 66160, USA. Tel 913-945-6630. salothman@kumc.edu.
Most patients undergoing lower extremity amputation (LEA) for diabetes had prior risk factors like neuropathy, peripheral vascular disease (PVD), or foot ulcers. These findings highlight the need for enhanced prevention strategies to reduce amputation rates.
Area of Science:
- Medical research
- Diabetology
- Vascular surgery
Background:
- Diabetic lower extremity amputation (LEA) is a significant complication.
- Identifying pre-amputation risk factors is crucial for prevention.
Purpose of the Study:
- To determine the frequency of neuropathy, peripheral vascular disease (PVD), and foot ulceration in diabetic patients before LEA.
Main Methods:
- Retrospective electronic health record review of diabetic patients who underwent LEA.
- Analysis of diagnosis codes for neuropathy, PVD, and foot ulcers preceding LEA.
Main Results:
- Of 844 patients, 79.3% had at least one risk factor before LEA.
- Prevalence: neuropathy (49.1%), foot ulcer (47.6%), PVD (58%).
- 23.6% had all three risk factors.
Conclusions:
- The majority of LEAs in diabetic patients are associated with pre-existing risk factors.
- Findings support escalating preventive measures for patients with these risk factors.
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