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Updated: Feb 5, 2026

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments
Published on: May 26, 2019
MRI-Linear Accelerator Radiotherapy Systems
G P Liney1, B Whelan2, B Oborn3
1Ingham Institute for Applied Medical Research, Department of Medical Physics, Liverpool, Australia; Liverpool Cancer Therapy Centre, Radiation Physics, Liverpool, Australia; University of New South Wales, School of Medicine, Sydney, Australia; Centre for Medical Radiation Physics, University of Wollongong, Australia.
Abstract:
The desire to utilise soft-tissue image guidance at the time of radiation treatment has led to the development of several hybrid magnetic resonance imaging (MRI) linear accelerators (linacs). These systems have the potential to realise the benefits of MRI on the treatment table with the ability of real-time motion management and adaption on a patient-specific basis. There are several MRI-linacs currently being implemented covering both low and high magnetic field strength and two beam-field orientations. Clinical trials have only recently begun with this technology, but their future use as standard radiotherapy practice seems assured. This review article summarises the challenges faced in developing such hybrid technology, the differences and advantages of each of the currently exploited solutions, and their current status.
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