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The Challenges of Using MRI During Radiotherapy.
A McWilliam1, B Rowland1, M van Herk1
1Division of Clinical Cancer Science, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK; Department of Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK.
Clinical Oncology (Royal College of Radiologists (Great Britain))
|September 11, 2018
Summary
This article explores integrating magnetic resonance imaging (MRI) into radiotherapy. It discusses MRI for better tumor outlining, MRI-only approaches, and functional imaging, highlighting implementation challenges for safe use.
Area of Science:
- Medical Physics
- Radiotherapy Technology
- Diagnostic Imaging
Background:
- Magnetic Resonance Imaging (MRI) offers superior soft-tissue contrast compared to traditional methods.
- Integrating advanced imaging into radiotherapy workflows is crucial for treatment precision.
- Current radiotherapy planning often relies on computed tomography (CT) which has limitations in soft-tissue visualization.
Purpose of the Study:
- To outline key considerations for incorporating MRI into radiotherapy workflows.
- To explore the benefits and challenges of MRI-based tumor delineation.
- To discuss the feasibility and implications of MRI-only radiotherapy.
Main Methods:
- Review of current literature on MRI applications in radiotherapy.
- Analysis of technical and clinical challenges in MRI integration.
- Discussion of functional imaging techniques (e.g., diffusion-weighted imaging) for radiotherapy.
Main Results:
- MRI enables more accurate tumor and organ-at-risk delineation, potentially improving treatment targeting.
- MRI-only workflows present opportunities for reduced imaging dose and streamlined planning but require robust technical solutions.
- Functional MRI techniques show promise for assessing treatment response and adapting radiotherapy plans.
Conclusions:
- Successful integration of MRI into radiotherapy requires addressing technical, safety, and workflow challenges.
- MRI-only workflows are a developing area with significant potential for advancing radiotherapy.
- Further research and standardization are needed to fully leverage MRI's capabilities in radiation oncology.
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