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Updated: Feb 5, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
[Risk factors of regional lymph node metastases in pT1 colorectal cancer]
S V Chernyshov1, Yu A Shelygin2, V N Kashnikov1
1Ryzhikh State Research Center of Coloproctology of Healthcare Ministry of Russia, Moscow, Russia.
Aim:
To identify risk factors of lymph node metastases in patients with pT1 rectal cancer.
Material And Methods:
There were 43 patients aged 62.3±11.3 years with pT1 rectal cancer who underwent mesorectal excision in 2012 - 2018. There were 34 (64%) females and 19 (36%) males.
Results:
Histological examination revealed SM1-2 in 22/43 (51%) cases, SM3 - in 21/43 (49%) cases. Lymph node metastases were identified in specimens with submucosal invasion: SM3 - in 8/21 (38.1%) cases and SM1-2 - in 3/22 (13.6%) cases (p=0.08). Logistic regression confirmed lymphovascular invasion (p=0.005) and mucosal and/or poorly differentiated carcinoma (p=0.014) as independent predictors of lymph node metastases.
Conclusion:
Lymphovascular invasion and poorly differentiated carcinoma are indications for transabdominal mesorectal excision.
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