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Infectious Bronchitis Virus Nonstructural Protein 4 Alone Induces Membrane Pairing.

Nicole Doyle1, Benjamin W Neuman2, Jennifer Simpson3

  • 1The Pirbright Institute, Pirbright, Surrey GU24 0NF, UK. nicole.doyle@pirbright.ac.uk.

Viruses
|September 12, 2018
PubMed
Summary

Infectious bronchitis virus (IBV) non-structural protein 4 (nsp4) alone induces membrane pairing, a key step in coronavirus replication. However, other viral or host factors are needed for full replication organelle formation.

Keywords:
coronaviruselectron tomographyinfectious bronchitis virusmembrane rearrangementsnon-structural proteinnsp3nsp4paired membraneszippered ER

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