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Spindle Assembly: Two Spindles for Two Genomes in a Mammalian Zygote
Adel Al Jord1, Marie-Hélène Verlhac1
1CIRB, Collège de France, and CNRS-UMR7241 and INSERM-U1050, Equipe Labellisée FRM, Paris F-75005, France.
Current Biology : CB
|September 12, 2018
Abstract:
A single bipolar spindle was thought to form around both parental genomes in zygotes initiating the first division. A recent study challenges this predominant view by showing that two independent spindles assemble to prevent parental genome mixing in mouse zygotes.
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