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Yellow Nail Syndrome Patients with Diffuse Panbronchiolitis-like Pulmonary Manifestation
Ryosuke Imai1, Ryo Nakatani2, Hiroshi Nakaoka3
1Division of Pulmonary Medicine, Thoracic Center, St. Luke's International Hospital, Japan.
Abstract:
Yellow nail syndrome (YNS) is a rare clinical syndrome characterized by a triad of yellow thick nail, lymphedema and respiratory diseases. We experienced 2 cases of YNS with diffuse panbronchiolitis (DPB)-like pulmonary manifestation. Since YNS might be hidden to those who have been diagnosed with DPB, physicians should be alert to recognize nail signs of YNS in case of DPB refractory to macrolide therapy. We hereby review previous case reports of YNS and discuss its pulmonary manifestations.
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