Related Experiment Video
Updated: Feb 5, 2026

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
Prognosis of FTC compared to PTC and FVPTC: findings based on SEER database using propensity score matching analysis
Zeming Liu1, Wen Zeng2, Lei Huang1
1Department of Plastic Surgery, Zhongnan Hospital of Wuhan University Wuhan 430071, Hubei Province, China.
Abstract:
The significance of prognosis of follicular thyroid cancer (FTC) compared to other subtypes of thyroid cancer, based on large cohort data has only been addressed in a few studies, and the results remain controversial. In this study, we investigated the prognosis of FTC compared to papillary thyroid carcinoma (PTC) and follicular variant PTC (FVPTC) based on Surveillance, Epidemiology, and End Results database (SEER) Program data using propensity score matching. We evaluated data from 128,703 patients with thyroid cancer who were included in the SEER database between 2004 and 2013. Patient mortality was evaluated using Cox proportional hazards regression analyses and Kaplan-Meier analyses with log-rank tests. The average prognosis of FTC was poorer than both PTC and FVPTC. The multivariate Cox regression analysis revealed that the cancer-specific survival rate for FTC was lower than that for PTC and FVPTC without adjusting for risk factors. Furthermore, after propensity score matching analysis for relevant factors, the cancer-specific mortality rate for FTC was higher than that for PTC and FVPTC. These results based on a large population cohort database provide a benefit reference for individual and precise treatment and management of patients with FTC.
Related Concept Videos
Comparing the Survival Analysis of Two or More Groups
Sign Test for Matched Pairs
To conduct the sign test, we first calculate the differences in...
Introduction to z Scores
z scores...
Introduction to z Scores
z scores...
z Scores and Area Under the Curve
Finding the Center of Gravity

