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Cuffed Versus Uncuffed Endotracheal Tubes in Pediatrics: A Meta-analysis

Liang Chen1, Jun Zhang1, Guoshi Pan1

  • 1Department of Anesthesiology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Medical University of Anhui, No. 246 Heping Road, Hefei, 230011, Anhui Province, China.

Open Medicine (Warsaw, Poland)
|September 14, 2018
PubMed

Insights

Cuffed endotracheal tubes may be better for pediatric patients, as uncuffed tubes require more frequent changes. Other complications were similar between cuffed and uncuffed endotracheal tubes in this meta-analysis.

Area of Science:

  • Pediatric Anesthesiology
  • Critical Care Medicine
  • Respiratory Therapy

Background:

  • Cuffed and uncuffed endotracheal tubes are used in pediatric surgery and emergencies.
  • The optimal choice between cuffed and uncuffed endotracheal tubes for children remains debated.

Purpose of the Study:

  • To compare the application and outcomes of cuffed versus uncuffed endotracheal tubes in pediatric patients.

Main Methods:

  • A systematic literature search was conducted across PubMed, Web of Science, and Cochrane Library.
  • Included studies were clinical trials comparing cuffed and uncuffed endotracheal tubes in children.
  • Data were summarized by independent reviewers, and a meta-analysis was performed using Revman 5.3 software.

Main Results:

  • The meta-analysis included 6 studies with 4141 pediatric patients.
  • Uncuffed endotracheal tubes led to a significantly higher need for tube changes (OR: 0.07, P < 0.00001).
  • No significant differences were found in intubation duration, reintubation, accidental extubation, croup, racemic epinephrine use, laryngospasm, or stridor.

Conclusions:

  • Uncuffed endotracheal tubes are associated with an increased requirement for tube changes in pediatric patients.
  • No significant differences in other major complications were observed between cuffed and uncuffed endotracheal tubes.
  • Cuffed endotracheal tubes may represent a more optimal choice for pediatric airway management, warranting further investigation.
Abstract

Keywords:
ChildrenCuffedEndotracheal tubeMeta-AnalysisUncuffed

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