Related Experiment Video
Updated: Feb 5, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Mantle cell lymphoma with involvement of the digestive tract
F M Oña-Ortiz1, J Sánchez-Del Monte1, M E Ramírez-Solís1
1Departamento de Endoscopia Gastrointestinal, Instituto Nacional de Cancerología, Secretaría de Salud, Ciudad de México, México.
Introduction And Aim:
Mantle cell lymphoma is an aggressive subtype of B-cell non-Hodgkin lymphoma and its incidence is 0.5/100,000 inhabitants. Gastrointestinal involvement at diagnosis is 15-30%. The aim of our study was to analyze the clinical and endoscopic characteristics of mantle cell lymphoma affecting the digestive tract.
Material And Methods:
A retrospective study was conducted, based on a case series of patients with mantle cell lymphoma affecting the gastrointestinal tract that were diagnosed over a 10-year period.
Results:
Ten patients (11.7%) had gastrointestinal tract involvement. The upper endoscopic findings were polypoid lesions (66%), thickened folds (44%), and nonspecific changes in the mucosa (33%). At colonoscopy, polypoid lesions were viewed in 100% of the patients and ulcerated lesions in 40%.
Conclusion:
Polypoid lesions are the most common endoscopic characteristics in patients with mantle cell lymphoma of the gastrointestinal tract. Upper endoscopy and colonoscopy should be carried out on patients with mantle cell lymphoma, even those with nonspecific symptoms, to check their gastrointestinal status. Gastrointestinal involvement has an impact on disease staging.
Related Concept Videos
What is Monogastric Digestion?
Carbohydrate Digestion
Lipid Digestion
Protein Digestion
Regulation of the Digestive System
The effectors in this regulation system are glands and smooth muscles. Activation of...
Other Disorders of Digestive System

