FGF23 beyond Phosphotropic Hormone

Yuichi Takashi1, Seiji Fukumoto2

  • 1Diabetes Therapeutics and Research Center, Institute of Advanced Medical Sciences, Tokushima University, 3-18-15 Kuramoto-cho, Tokushima, Tokushima 7708503, Japan; Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, 3-18-15 Kuramoto-cho, Tokushima, Tokushima 7708503, Japan.

Summary

Fibroblast growth factor (FGF) 23 regulates phosphate and vitamin D. This review explores FGF23 actions beyond the kidney, particularly its α-Klotho-independent roles in other tissues under disease conditions.

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