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Updated: Feb 5, 2026

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
[Complex regional pain syndrome]
1Abteilung für Unfall‑, Hand- & Wiederherstellungschirurgie, Klinik und Poliklinik für Chirurgie, Universitätsmedizin Rostock, Schillingallee 35, 18057, Rostock, Deutschland. philipp.herlyn@med.uni-rostock.de.
Abstract:
Complex regional pain syndrome (CRPS) is not a very common yet typical complication of extremity trauma in the daily practice of a trauma surgeon. The pathophysiology of this puzzling disease is still not completely understood and its impact on the patient cannot be overestimated. However, advantages have been made in diagnostics and therapy. While a multitude of different diagnostic systems has led to confusion in the past, we now have an internationally accepted, validated and easy to reproduce diagnostic algorithm in the form of the Budapest criteria. The adequate therapy is still a field for debate, but there is now a broad choice of conservative and interventional treatments for the out- and inpatient setting.
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