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Updated: Feb 5, 2026

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
Free gingival graft adjunct with low-level laser therapy: a randomized placebo-controlled parallel group study
Mehmet Selim Yildiz1, Sadiye Gunpinar2
1Department of Periodontology, Faculty of Dentistry, Abant Izzet Baysal University, Bolu, Turkey.
Low-level laser therapy (LLLT) reduced free gingival graft (FGG) shrinkage and postoperative pain. This therapy offers additional benefits for FGG procedures, improving patient outcomes and graft stability.
Area of Science:
- Periodontology
- Regenerative Medicine
- Biophotonics
Background:
- Free gingival graft (FGG) procedures are common in periodontology.
- Graft shrinkage and postoperative pain are significant challenges.
- Low-level laser therapy (LLLT) is explored for its regenerative potential.
Purpose of the Study:
- To evaluate the efficacy of LLLT in conjunction with FGG procedures.
- To assess LLLT's impact on FGG shrinkage and wound healing.
- To determine LLLT's effect on postoperative pain reduction.
Main Methods:
- A randomized controlled trial involving 30 patients undergoing FGG.
- Patients received either FGG + LLLT (test group) or FGG + placebo LLLT (control group).
- An 810-nm diode laser was applied post-surgery, with measurements taken at baseline and 3, 6 months.
Main Results:
- Graft shrinkage was significantly lower in the LLLT group at 3 and 6 months (p<0.05).
- No significant difference in wound epithelialization was observed between groups.
- LLLT significantly reduced VAS pain scores and analgesic use (p<0.05).
Conclusions:
- 810-nm diode laser therapy enhances FGG outcomes by reducing graft shrinkage.
- LLLT effectively alleviates postoperative pain following FGG procedures.
- LLLT offers additional benefits for FGG, improving graft stability and patient comfort.
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