MR Imaging of Joint Infection and Inflammation with Emphasis on Dynamic Contrast-Enhanced MR Imaging

Mikael Boesen1, Olga Kubassova2, Iwona Sudoł-Szopińska3

  • 1Department of Radiology, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400, Copenhagen Nv, Denmark; Parker Institute, Bispebjerg and Frederiksberg Hospital, Nordrefasanvej 57, 2000 Copenhagen F, Denmark.

PET Clinics
|September 17, 2018
PubMed

Insights

Dynamic contrast-enhanced MR imaging (DCE-MR imaging) enhances the diagnosis of joint infections and inflammatory diseases. This technique quantifies blood flow and capillary permeability for improved assessment.

Area of Science:

  • Radiology and Medical Imaging
  • Musculoskeletal Imaging
  • Infectious Disease Imaging

Background:

  • Contrast-enhanced MR imaging (CE-MR imaging) is crucial for diagnosing and monitoring joint infections and inflammatory conditions.
  • CE-MR imaging effectively distinguishes between soft tissues, bone, fluid collections, and infectious debris.

Purpose of the Study:

  • To describe the principles of dynamic CE-MR imaging (DCE-MR imaging) for assessing infectious and inflammatory joint diseases.
  • To highlight the utility of DCE-MR imaging in improving diagnostic information beyond standard CE-MR imaging.

Main Methods:

  • Utilizes fast T1-weighted sequential image acquisition during contrast agent injection.
  • Employs dedicated analysis methods and software for contrast kinetic analysis.
  • Focuses on quantitative extraction of information on blood flow and capillary permeability.

Main Results:

  • DCE-MR imaging provides quantitative data on perfusion and vascular permeability in joint tissues.
  • This quantitative information enhances the characterization of infectious and inflammatory processes.
  • Dedicated software enables robust analysis of contrast agent kinetics.

Conclusions:

  • DCE-MR imaging offers advanced insights into the pathophysiology of infectious and inflammatory joint diseases.
  • The quantitative assessment of blood flow and capillary permeability improves diagnostic accuracy and monitoring capabilities.
  • This technique represents a valuable advancement in musculoskeletal MR imaging for inflammatory and infectious conditions.

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